Words similar to colorectal
Example sentences for: colorectal
How can you use “colorectal” in a sentence? Here are some example sentences to help you improve your vocabulary:
BMD also reflects exposure to calcium and to physical activity as well as foods affecting calcium absorption and deposition [ 7 8 9 ] . All of these factors, including estrogen, are thought to diminish the risk of colorectal cancer [ 10 11 ] . On the other hand increased calcium intake has been associated with increased risk of prostate cancer [ 12 13 ] . Because of the intimate association of BMD with to all of these exposure variables, BMD needs to be examined in relation to each of these cancers.
However, a comparison of hazard ratios by cause of death showed that the values were much lower for death due to colorectal cancer than for other causes.
M6P/IGF2R loss of heterozygosity occurs frequently in human breast, liver and lung cancer [ 6 20 21 22 ] , and the remaining allele of 30 to 50% of these tumors contains an intragenic loss-of-function point mutation in the ligand binding domains [ 35 ] . The M6P/IGF2R is also commonly mutated in gastrointestinal and endometrial malignancies because its coding sequence contains a poly-G region that is a mutational target in tumors with mismatch repair deficiencies and microsatellite instability [ 23 24 ] . Functional studies show that the introduction of an exogenous wild-type M6P/IGF2R into human colorectal cancer cells with a single inactivated allele significantly decreases growth rate and enhances apoptosis [ 26 ] . Conversely, loss of M6P/IGF2R expression promotes cancer cell growth by increasing intracellular signaling from both the insulin-like growth factor I receptor and the insulin receptors [ 36 ] .
We speculate that co-morbid illness might play a role in treatment selection for some individuals with colorectal cancer.
In addition, there have been 8 studies of vitamin D intake, only 3 of which have shown decreased colorectal cancer risk related to increased vitamin D [ 25 ] .
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