Example sentences for: colocalization

How can you use “colocalization” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • It is to be expected that with greater stimulation time the colocalization would increase, which presents the prospect of studying the relative dynamics of AChR and α-DG colocalization.

  • Tomographic analysis was chosen because it enables quantitative three-dimensional examination of fine structure within the relevant mitochondrial domains in semi-thick sections and thereby facilitates accurate representation of the sometimes complex membrane topology of this organelle [ 11 12 ] . Immunoelectron tomography is ideal for testing the independence of two types of labels, or label and structural component (as employed in this study), and their deviation from independence - colocalization or mutual inhibition - because it allows true 3-D distances to be measured.

  • Previous reports have found colocalization of these molecules in areas of tissue remodeling, loosening of prosthetic joints [ 45, 46, 47], and in the cartilage-pannus junction [ 14].

  • Figure 3) that there is less perfect colocalization of α-DG within AChR aggregates in the present study than reported previously (see for example [ 4 ] Figure 9 for a comparable study using Xenopus muscle cell cultures).

  • This putative association is strengthened by finding for the first time that targeting of RIα requires the AKAP binding surface [ 17 ] . Yotiao is another AKAP enriched at the NMJ, but appears to bind only RII [ 30 ] . PKA phosphorylates the nAChR when stimulated at the synapse by the neuropeptide CGRP and by adenosine from muscle responding to acetylcholine [reviewed by [ 31 ] ]. This phosphorylation may regulate the degradation of the nAChR [ 32 ] . Consistent with the action at the presynapse, it was shown that PKA facilitation of acetylcholine release is dependent on nerve endplate calcium concentration [ 33 ] . Based on our observation of colocalization with synaptophysin at presynaptic vesicles, RIα may be the isotype that influences this release of neurotransmitter.


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