Words similar to colchicine

Example sentences for: colchicine

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The expression of genes encoding α-tubulin and β-tubulin seems to be developmentally regulated [ 19 ] . For example, tubulin isotype expression patterns change during the development and maturation of neurons [ 14 20 ] . Studies with paclitaxel or other antimitotic agents, such as colchicine or estramustine, indicate that drug interactions with tubulin isotypes differ [ 21 22 23 24 25 ] and might contribute to cell resistance to antimitotics [ 26 27 28 29 30 31 ] . However, one group of antimitotic agents, the vinca alkaloids, was shown to bind with similar affinity to all tubulin isotypes [ 12 ] , suggesting that alterations in drug binding affinity is unlikely to be the cause of drug resistance.
By contrast, in humans, we found NK-ir perikarya located in the dorsal motor nucleus of the vagus, in which in the cat no immunoreactive cell bodies were found [ 15 ] . The differences observed in both species concerning the distribution of cell bodies containing NK could be due to technical considerations, since in the cat colchicine was administered in the fourth ventricle in order to accumulate the peptide in cell bodies [ 15 ] .