Example sentences for: cohesin

How can you use “cohesin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • It is currently unclear why the cell has two mechanisms to dissociate cohesin from chromosomes, although it is interesting to speculate that this could be related to different functions of cohesin at chromosome arms versus pericentric domains.

  • This model further speculates that rather than Cornelia de Lange syndrome stemming from a cohesin loading defect, the failure to unload cohesin from regions that need to be transcribed leads to transcriptional defects that cause the syndrome.

  • Indeed, the chromatin remodeling complex RSC (remodels the structure of chromatin) has been shown to be important for establishment of cohesin binding [42], and another study suggests RSC is particularly important for cohesin association with chromosome arms [43].

  • In this issue of PLoS Biology , one of two related papers exploring the regulation of cohesin in vertebrates shows that phosphorylation of Scc3 (SA2) by Polo-like kinase is apparently sufficient to allow dissociation from chromosome arms, which occurs during prophase [32].

  • also supports the idea that chromatin modification/structure is a key determinant of cohesin localization [46,47].


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