Words similar to cognate
Example sentences for: cognate
How can you use “cognate” in a sentence? Here are some example sentences to help you improve your vocabulary:
To select a threshold, we have exploited a reference set of positive and negative control genes based on presence or absence of their cognate labeled cDNAs in the hybridization mix.
To examine further the relationship between putative nodL candidates found in M. incognita and M. javanica with the cognate genes in rhizobia, we undertook a phylogenetic analysis and found that the two nematode genes fall squarely within the rhizobial nodL clade (Figure 2).
Aminoacyl-tRNA synthetases catalyze a succession of reactions, which involve: hydrolysis of the α-β phosphate bond in ATP; condensation of AMP with the cognate amino acid, resulting in the formation of an aminoacyl-adenylate; displacement of the AMP moiety of the aminoacyl-adenylate with the cognate tRNA, producing aminoacyl-tRNA.
A recent study identified a number of α5 helix residues in α t that when changed to alanines increased rates of guanine-nucleotide exchange ( i.e., decreased affinity for guanine-nucleotides) [ 5 ] . Individual mutation of amino acids in α t , cognate to T330, N332, V333, F337 in α i2 (Figure 1), increased nucleotide exchange rates [ 5 ] . Two of these critical amino acids, N332 and V333 in α i2 , are in fact the first two amino acids that are replaced by the novel splicing in sα i2 (Figure 1).
In vitro, purified EPKs often display broad protein substrate specificity [ 7], and it is thought that in many cases in vivo substrate specificity is limited by a requirement for substrate to associate not only with its cognate EPK, but also with other components of an EPK-containing protein assembly [ 8, 33, 34].
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