Example sentences for: cognate

How can you use “cognate” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Amino acid substitutions at the position cognate to N116 in H-Ras typically yield soluble Rab proteins that have a reduced affinity for guanine nucleotides.

  • Elevated TNFα activity may play a role in the apoptosis of CL-derived microvascular endothelial (CLENDO) cells [ 29 ] . TNFα is known to initiate apoptosis in diverse cell types by activating its cognate receptor, TNF-RI, a cell surface receptor and member of the tumor necrosis receptor super family (TNFRSF).

  • The background is very similar between the images, but the fluorescence intensity of the spots is greatly reduced as the partial and absolute concentration of the cognate antibodies decreases.

  • In the absence of cognate hormone, several nuclear receptors actively repress transcription of target genes via interactions with the nuclear receptor corepressors SMRT and NCoR.

  • Several laboratories have shown that in addition to mutations in the N(T)KxD motif, which reduce overall nucleotide binding, dominant-negative Rab constructs can be generated by introducing amino acid substitutions ( e.g. , asparagine) at the position cognate to Ras S17 ( i.e. , S22 in Rab24) [ 31 40 41 42 ] . Such proteins are thought to be locked in an inactive GDP-bound state because the mutation markedly reduces their affinity for GTP, compared to GDP [ 42 ] . As shown in Fig.


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