Example sentences for: coenzyme

How can you use “coenzyme” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In the case of pNPP hydrolysis, others have reported both saturated and unsaturated fatty acyl coenzyme A esters stimulate PP5 activity, with concentrations required for half-maximal stimulation approximately 10-fold lower than those of their corresponding free fatty acids [ 21 ] . We therefore tested whether a saturated fatty acyl coenzyme A ester could also stimulate Ppt1p.

  • Unlike PP5, the activity of Ppt1p toward 32P-casein was not stimulated by AA, arachidoyl coenzyme A, or linoleoyl coenzyme A over a range in concentration from 10-500 μM (Fig.

  • Statins, potent compounds that inhibit cholesterol synthesis in the liver by blocking 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA), have been reported to induce osteoblast activity and lead to bone formation, both in tissue culture and in rats and mice [ 1 2 3 4 5 6 ] . These findings, if confirmed and extended to include humans, have the potential to introduce immediate new treatment options to patients with low bone mass and osteoporosis.

  • Patients on dialysis have more coronary artery disease (CAD) and CAD-related mortality than the general population [ 1 ] . Elevated low-density lipoprotein (LDL) cholesterol level is an independent risk factor for patients with end stage renal disease (ESRD) [ 2 ] . The 3-hydroxy-3methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) have been associated with decreased all-cause mortality in dialysis patients in a registry-based study [ 3 ] and clinical trials are underway to confirm this benefit [ 4 5 ] .

  • HMG CoA = 3-Hydroxy-3-methylgluatryl coenzyme A; MIRACL = Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering; LDL = low density lipoprotein; RR = relative risk; CI = confidence interval; HDL = high density lipoprotein; PTCA = percutaneous transluminal coronary angioplasty; CABG = coronary artery bypass graft; ECG = electrocardiogram; A-2-Z = Aggrastat to Zocor; ACS = acute coronary syndrome; PROVE IT = Pravastatin or Atorvastatin Evaluation and Infection Therapy.


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