Words similar to coenzyme
Example sentences for: coenzyme
How can you use “coenzyme” in a sentence? Here are some example sentences to help you improve your vocabulary:
Three published [ 1 2 3 ] and one recently presented [ 4 ] randomized placebo-controlled clinical trial have unequivocally demonstrated that 3-Hydroxy-3-methylgluatryl coenzyme A (HMG CoA) reductase inhibitors (statins) reduce the morbidity and mortality associated with coronary disease.
Acl exhibits strong similarity to coenzyme F390 synthetase of methanogenic archaea, as well as to phenylacetate-CoA ligase of E. coli . As Xylella does not appear to make the F420 cofactor that is the substrate of F390 synthetase, the function of Acl is likely to be closer to phenylacetate-CoA ligase.
Ppt1p activity toward 32P-MBP was stimulated by arachidoyl coenzyme A in a concentration range similar to that observed for AA, with half-maximal stimulation occurring at approximately 50 μM for arachidoyl coenzyme A and 75 μM for AA.
Others have proposed that fatty acyl coenzyme A esters are potential physiologic regulators of PP5, since these compounds stimulate pNPP hydrolysis by PP5 in vitro at physiologically relevant concentrations and are approximately 10-fold more potent than their free fatty acid counterparts [ 21 ] . Although we confirmed this observation using PP5 and pNPP (data not shown), in our hands similar levels of AA and arachidoyl coenzyme A were required for half-maximal stimulation of 32P-MBP dephosphorylation in the case of both Ppt1p and PP5.
Although more work is required to examine this issue thoroughly, our results suggest that the large differences in potency between free fatty acids and fatty acyl coenzyme A esters seen using pNPP may not extend to all protein substrates.
Loading...