Words similar to codon
Example sentences for: codon
How can you use “codon” in a sentence? Here are some example sentences to help you improve your vocabulary:
We conclude that the additional AZT resistance conferred by codon 219 mutations did not provide significant selective advantage to the profiled HIV viruses, possibly because HIV had already acquired the maximum effective AZT resistance selectable, in vivo , when mutations arose at this codon.
Sickle cell anemia (Hb SS) results from homozygosity for a A→T substitution at codon 6 of the β-globin gene (GAG→GTG) leading to a glutamic acid to valine (Glu→Val) substitution in the β globin chain of human adult hemoglobin.
Any other ttt codon will have its own selective pressures assessed in a similar but independent testing procedure.
The CaCET1 gene was disrupted by insertion of a UAU1 cassette [ 16 ] . We first constructed plasmid pKS-5'3'CaCET1, in which a 665-bp PCR fragment derived from the 5' end of the CaCET1 gene (from nucleotides -50 to +615 of the open reading frame, with the A residue of the ATG translation start codon defined as position +1) was cloned between the Kpn I and Xba I sites of pBluescript KS +and a 720-bp fragment extending from position +1518 of the 1560-nt CaCET1 coding sequence into the 3' flanking genomic region was inserted between the Sac I and Sac II sites of pBluescript KS +The 3.8-kbp UAU1 gene was excised from pBME101 with Xba I and Sac II and inserted between the Xba I and Sac II sites of pKS-5'3'CaCET1 to yield pCaCET1::UAU1.
For sequence analysis, the prospects are more promising: given very limited information about a species (the GC content), it may be possible to estimate the codon usage and therefore minimize the degeneracy of PCR primers, even if no closely related species have been characterized.
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