Words similar to cochlear
Example sentences for: cochlear
How can you use “cochlear” in a sentence? Here are some example sentences to help you improve your vocabulary:
The long term retention of afferents in the cochlear apex in the absence of any apparent differentiation of hair cells raises hopes for cochlear implants in deaf-born children.
MX generated the null mutation, bred all the mice used for this study and generated the statistical data and the immunocytochemical data with MyoVII, AM conducted the tract tracing studies of cochlear afferents and helped with the histological analysis and assembly of image plates, UP carried out the in situ hybridization for neurotrophins and assembled the plates for these data, BF wrote the manuscript, carried out most of the neuronal tracing and immunocytochemistry for acetylated tubulin and data presentation.
Immunostaining of P7 cochlear whole mounts using the hair cell specific-myosin VII (MyoVIIa) antibody was performed as previously described [ 2 ] . Images of labeled organs of Corti were then acquired using a SPOT digital camera (Diagnostic Instruments Inc.) and the number of hair cells was scored from acquired images.
The comparatively high level of NT-3 expression in Brn3c null mutant cochlea, which has been shown to be the neurotrophin most prominently supporting spiral sensory neurons [ 6 9 14 ] , is in agreement with the normal development of cochlear innervation in newborn Brn3c null mutants.
Mutations in TMC1 are responsible for the autosomal dominant human hearing disorder DFNA36 and for the recessive deafness DFNB7/11 [ 5 ] ; the corresponding murine gene Tmc1 also causes deafness in the mutant mouse strains Beethoven ( Bth ) and deafness ( dn ) [ 6 ] . Bth / Bth mice display altered potassium currents in early postnatal cochlear hair cells, in particular Ik,n and Ik,f currents appear to be depressed [ 10 ] . This observation led to the hypothesis that Tmc1 may participate directly or indirectly in regulating the permeability of potassium channels [ 10 ] . Because of the high level of conservation of the amino acid sequences among the eight mammalian TMC proteins (Figure 1, Additional file 1), we speculate that other TMC proteins may as well be modifiers of ion channels or transporters.
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