Words similar to cobblestone
Example sentences for: cobblestone
How can you use “cobblestone” in a sentence? Here are some example sentences to help you improve your vocabulary:
The town itself — declared a national monument in 1928 — is one of the most picturesque in the country, with narrow, winding cobblestone streets that pass white stucco buildings topped with red-tile roofs, and adorned with flowers tumbling from window boxes.
Tat has been shown to down-regulate mannose receptor, EDF-1, CD3-gamma, and TCR/CD3 surface receptor [ 14 ] . Tat reduces mannose receptor levels and promoter activity in mature macrophages and dendritic cells by interfering with the host transcriptional machinery; resulting in decreased levels of surface mannose receptor needed for Ag (mannosylated albumin uptake) or pathogen capture (Pneumocystis carinii phagocytosis), and eventual delivery to MHC class II-containing intracellular compartments [ 15 ] . EDF-1, a gene down-regulated when endothelial cells are induced to differentiate in vitro , was shown to be down-regulated by Tat at the transcriptional level, resulting in the inhibition of endothelial cell growth and in the transition from a nonpolar cobblestone phenotype to a polar fibroblast-like phenotype [ 16 ] .
With its cobblestone courtyard, it looks like a picturesque country pub, and seems to be a must for every visitor.
The town itself has a picture-postcard appeal — whitewashed houses with red-tile roofs and balconies filled with flowers sit along neat rows of cobblestone streets — and the residents here are renown for their gentle friendliness and understated hospitality.
Once a fruit and vegetable market, the cobblestone square remains a favorite venue for flower-vendors and itinerant artists.
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