Words similar to co-mobilized
Example sentences for: co-mobilized
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A proposed consequence of L1 3' transduction is exon shuffling [ 28 33 34 ] . That is, an exon downstream of an L1 may be co-mobilized with that same L1 and inserted at a new locus such that the exon is integrated into another gene.
demonstrated this experimentally in cultured cells by cloning a reporter gene containing a splice acceptor downstream from the polyadenylation signal of an intact L1 element [ 28 ] . This engineered L1 retrotransposed into transcriptionally active genomic loci, allowing the co-mobilized reporter to be expressed after being spliced into a transcript expressed in these cells, effectively creating a chimeric mRNA [ 28 ] .