Example sentences for: co-localization

How can you use “co-localization” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Our recent studies have revealed the co-localization of maspin and WT-1 exclusively in mammary ME cells [ 12 ] . In a vast majority of cases, the expression of these two proteins decreases linearly with tumor progression, and the loss of these proteins or focal disruptions in the ME cell layers leads to a significantly higher cell proliferation in the subjacent epithelial cells [ 12 33 ] . In addition, these changes in ME cells could result from effects of certain chemical compounds.

  • For example, statins have been proposed to cause co-localization of α-secretase and APP within lipid rafts [15,33]; statins might also induce modification of the structure and activity of a protein in the plasma membrane α-secretase complex, perhaps in an action similar to how statins bind and “lock” cell-surface integrins [34].

  • We therefore analyzed mitotic cells, but did not observe co-localization of TOP1 and the BTBDs (not shown).

  • 5, nearly complete co-localization was again observed for both antigens.

  • We then tested for co-localization in transfected cells.


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