Words similar to co-localization
Example sentences for: co-localization
How can you use “co-localization” in a sentence? Here are some example sentences to help you improve your vocabulary:
SLC/CCL21, a CC chemokine expressed in high endothelial venules and in T cell zones of spleen and lymph nodes, strongly attracts naive T cells and DCs [ 1 2 3 4 5 6 7 8 ] . Because DCs are potent APCs that function as principal activators of T cells, the capacity to facilitate the co-localization of both DC and T cells may reverse tumor-mediated immune suppression and orchestrate effective cell-mediated immune responses [ 9 10 25 26 27 ] . In addition to its immunotherapeutic potential, SLC/CCL21 has been found to have potent angiostatic effects [ 28 ] , thus adding further support for its use in cancer therapy.
The strength of protein interactions (with DNA) has been measured on chips in a highly parallel manner [ 39 ] and the same could be done for protein-protein interactions [ 40 ] . Data on the spatial and temporal co-localization of signaling components is being generated by new imaging techniques [ 41 ] , which will yield insight into the mechanism with which the cellular response to a signal is modulated by the intensity and the duration of the signal [ 42 ] , and the interplay with parallel pathways.
Our recent studies have revealed the co-localization of maspin and WT-1 exclusively in mammary ME cells [ 12 ] . In a vast majority of cases, the expression of these two proteins decreases linearly with tumor progression, and the loss of these proteins or focal disruptions in the ME cell layers leads to a significantly higher cell proliferation in the subjacent epithelial cells [ 12 33 ] . In addition, these changes in ME cells could result from effects of certain chemical compounds.
Furthermore, CD98 association with β1 integrins appears to occur in the context of an ordered lipid microdomain (as evidenced by co-localization in light membrane fractions of sucrose density gradients), and appears to require the light chain of CD98.
Even when we require co-localization within 10 bp, we still retain 25% of the predictions originally selected to be within 500 bp.
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