Example sentences for: co-induced

How can you use “co-induced” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Several observations support the assertion that a complex interaction between IL-8 and several other growth factors, cytokines, or other proteins is responsible for these tumor-related events [ 5 9 10 11 12 13 ] . Growth regulated protein alpha (GRO-α), beta (GRO-β), and ENA-78 have been reported to be co-induced with IL-8 in A549 cells stimulated with two proinflammatory cytokines, IL-1β and TNF-α [ 14 ] . This result is consistent with the presence of nuclear factor kappa B (NF-κB) consensus binding sites in the promoter regions of all three genes [ 4 15 ] . In addition, GRO-α and -β are also members of the ELR +CXC cytokine family that are reported to be important mediators of tumorigenesis through their angiogenic properties [ 2 16 ] . They both share one of the IL-8 receptors, CXCR2, which has been postulated to regulate the ELR +CXC chemokine-mediated angiogenesis and resulting-tumorigenesis [ 1 ] . These observations suggest that GRO-α and -β may exhibit expression profiles similar to IL-8.

  • In the group of 50 co-induced genes in our example, we found that 101 terms were shared by at least two genes (according to our filtering criteria) with as many as 300 positive associations between genes and terms (defined as exceeding baseline occurrence by 25%).

  • Once in the nucleus, NFAT can bind DNA elements in target promoters, often in association with other resident and co-induced nuclear proteins [ 1].


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