Words similar to co-expression
Example sentences for: co-expression
How can you use “co-expression” in a sentence? Here are some example sentences to help you improve your vocabulary:
Two molecular loci recently have been implicated as potential modulators of GnRH receptor signaling: one is the receptor itself [ 23 ] , and the other is the G protein that transduces the signal generated by binding of the receptor to its agonist [ 9 ] . With respect to the former locus, G protein coupled receptor kinases (GRKs) act in an agonist-specific manner to phosphorylate intracellular regions of the receptor thus permitting β arrestin binding that sterically inhibits G protein association with the receptor [ 1 45 ] . We have reported previously that experimental expression of GRKs in GnRH receptor-expressing heterologous cells (COS-1) suppressed GnRH-stimulated IP 3 production, and that co-expression of GRK2 and β-arrestin 2 suppressed GnRH receptor signaling more than that of either alone [ 23 ] . Stronger evidence that the GRK/β arrestin paradigm may play a role in regulating GnRH receptor signaling is our recent finding that adenovirus-mediated gene transfer of GRK2 into normal pituitary gonadotropes suppressed GnRH-stimulated LH secretion and IP 3 production [ 31 ] . However, no evidence has been presented for a direct interaction between β-arrestin and the GnRH receptor.
However, co-expression of the Src KM/Cas(SD) chimera along with a SH2 mutant of v-crk demonstrated that an intact v-crk SH2 domain is required for association with the tyrosine phosphorylated Src KM/Cas(SD) (Fig.
To further examine the consequences of the interaction between Rlk and Src Family kinases, we examined tyrosine phosphorylation of Rlk by Fyn using co-expression studies.
However, the co-expression of ALK3Q233D allowed the detection of F-Az in SNIP1 immunoprecipitates (Fig.
4B, co-expression of pGal4-hCCR4 with either pVP16-hCAF1 or pVP16-hPOP2 elicited a significant increase (> 35 fold) in pG4-TK-Luc expression, thus demonstrating association between hCCR4 and either hCAF1 or hPOP2.
Loading...