Words similar to clendo

Example sentences for: clendo

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TNFα elevates ceramide in CLENDO cells, whereas sFasL elevates ceramide in primary luteal steroidogenic cells [ 26 ] . Ceramide treatment induces apoptosis in both cell types, suggesting that the sphingomyelin pathway may be a common mediator of cell death among distinct cell types within the CL.
To identify putative luteolytic factors that initiate CLENDO cell apoptosis, cells were treated with TNFα (50 ng/ml; Upstate Biotechnology, Inc.; Lake Placid, NY), bovine IFNγ (200 IU/ml; generous gift from Dr. Dale Godson, Veterinary Infectious Disease Organization, University of Saskatchewan, Saskatoon, Saskatchewan, Canada), sFasL (50 ng/ml; Oncogene, LaJolla, CA), mouse Fas activating antibody (Jo2; 500 ng/ml; Pharmingen, San Diego, CA), human Fas activating antibody (CH-11; 500 ng/ml; Upstate Biotechnology, Inc., Lake Placid, NY), PGF
Exogenous ceramide induced CLENDO cell oligonucleosomal DNA fragmentation and reduced cell viability in a manner consistent with TNFα treatment.
The amount of ceramide generated by CLENDO cells in response to TNFα treatment (50 ng/ml) was determined in three independent sets of experiments via the diacyl glycerol kinase assay as described [ 26 40 ] . Each experiment contained an untreated control that was used for comparison with TNFα treated samples.
In a second group of experiments, we observed that CLENDO cells were resistant to apoptosis when treated for 72 h with sFasL or the human Fas activating antibody CH-11.