Words similar to cleavage
Example sentences for: cleavage
How can you use “cleavage” in a sentence? Here are some example sentences to help you improve your vocabulary:
The greater than 2-fold increase in Caspase 3 activation is associated with a 1.8-fold increase in PARP cleavage (Fig.
For example, Herschlag and co-workers have previously shown that a nucleobase could complement an abasic site within the hammerhead ribozyme, restoring cleavage activity [ 1 ] . Similarly, Porta and Lizardi engineered a hammerhead ribozyme that assumed an inactive secondary structure; upon the addition of an oligonucleotide that disrupted the engineered secondary structure, the ribozyme was activated [ 2 ] . More recently, it has previously been shown that many selected nucleic acid binding species (aptamers) undergo conformational changes upon ligand binding [ 3 4 5 6 ] In addition, when aptamers are conjoined to ribozymes, the ligand-induced conformational changes in the aptamers frequently modulate the structures and hence the activities of the ribozymes [ 7 8 9 ] For example, binding of theophylline to the anti-theophylline aptamer [ 10 ] modulates the conformation of residue [ 11 12 ] and the overall stability of the aptamer [ 10 13 ] . Appending the anti-theophylline aptamer to the hammerhead ribozyme allowed cleavage activity to be modulated by 110-fold by theophylline [ 13 ] . Similarly, appending the anti-theophylline aptamer to a small ribozyme ligase (L1) generated an aptazyme that was activated 1,600-fold by saturating theophylline concentrations [ 14 ] .
The acidic enzyme activity is present in soluble SPAM1 that is generated during the acrosome reaction (AR), after cleavage at its carboxy terminus [ 9 ] . In primate sperm where SPAM1 is a 64-kDa protein, the proteolytically cleaved secretory form that is released after the AR is 53 kDa [ 9 ] .
Four regions of dividing cells were defined for analysis purposes: the cortex as a whole, the cytoplasm, the cortex underlying the cleavage furrow and the cortex underlying the poles (Figure 1).
Their subtler spin, well-expressed by Gerhart, is that Chastain "has brought instant attention to a piece of clothing that is humble and practical--not a traditional bra of shine and lace and cleavage, but a sturdy compression garment.
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