Words similar to clb

Example sentences for: clb

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In the absence of cycloheximide, Sic1 accumulated and Clb2 disappeared as cells exited mitosis (Figure 1, lanes 1-4).
We have previously shown that both net1 tab 2-1and CDC14 TAB 6-1efficiently bypassed the mitotic arrest caused by Tem1-depletion [ 15 18 ] . Furthermore, bypass was accompanied by ectopic Sic1 accumulation and Clb2 degradation.
Ectopic release of Cdc14 might contribute to the proliferation block and Clb2 degradation caused by induction of GAL-CDC5(DB▲) [ 19 20 ] . Overexpression of Cdc5(DB▲) also altered nucleolar structure in nocodazole-arrested cells (Figure 2B), the reason for which is not understood.
By counteracting Cdk1-mediated phosphorylations, Cdc14 activates both Hct1/Cdh1, which targets Clb2 for degradation [ 3 4 5 ] , and Swi5, which turns on the transcription of Cdk1 inhibitor Sic1 [ 6 3 ] . Degradation of Clb2 and accumulation of Sic1 act in concert to eliminate mitotic Cdk activity, which is required for exit from mitosis [ 7 ] . Thus, elucidating how Cdc14 is regulated holds the key to understanding how cells exit mitosis.
CLB analyzed data, took an active participation on the writing of all versions of the draft and approved the final version of the paper.