Words similar to clb

Example sentences for: clb

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Ectopic release of Cdc14 might contribute to the proliferation block and Clb2 degradation caused by induction of GAL-CDC5(DB▲) [ 19 20 ] . Overexpression of Cdc5(DB▲) also altered nucleolar structure in nocodazole-arrested cells (Figure 2B), the reason for which is not understood.
In the presence of cycloheximide, Sic1 accumulation was abolished, but Clb2 degradation still occurred with apparently normal kinetics (Figure 1, lanes 5-8 and 9-12).
Efficient bypass of mitotic arrest by both SIC1-dependent and SIC1-independent tabmutants is accompanied by ectopic Sic1 accumulation and Clb2 degradation
When cells harboring conditional-lethal temperature-sensitive (ts) mutations in any of these proteins are shifted to the restrictive temperature, they uniformly arrest in late anaphase as large-budded cells with segregated chromosomes, fully elongated microtubule spindles, and in all tested cases, elevated Cdc28/Clb2 protein kinase activity (Cdc28 is the major cyclin-dependent kinase Cdk1 and Clb2 the major mitosis-specific cyclin of budding yeast) (reviewed in [ 1 ] , [ 2 ] ).
dbf2Δ [ 22 7 ] . To address if production of new proteins is essential for exit from mitosis, we examined the effects of the protein synthesis inhibitor cycloheximide on Clb2 degradation, a key aspect of this process.