Words similar to clb
Example sentences for: clb
How can you use “clb” in a sentence? Here are some example sentences to help you improve your vocabulary:
When cells harboring conditional-lethal temperature-sensitive (ts) mutations in any of these proteins are shifted to the restrictive temperature, they uniformly arrest in late anaphase as large-budded cells with segregated chromosomes, fully elongated microtubule spindles, and in all tested cases, elevated Cdc28/Clb2 protein kinase activity (Cdc28 is the major cyclin-dependent kinase Cdk1 and Clb2 the major mitosis-specific cyclin of budding yeast) (reviewed in [ 1 ] , [ 2 ] ).
In the absence of cycloheximide, Sic1 accumulated and Clb2 disappeared as cells exited mitosis (Figure 1, lanes 1-4).
Having established that tab3-1 indeed bypassed Tem1 deficiency at a cellular level, we tested whether Sic1 accumulation and Clb2 degradation, two hallmark events that accompany exit from mitosis, also occurred.
In contrast, as Tem1-depleted tab3-1 cells progressed through mitosis, Clb2 was almost completely degraded and Sic1 accumulated to high levels (Figure 3B, right panels).
CLB analyzed data, took an active participation on the writing of all versions of the draft and approved the final version of the paper.
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