Words similar to cis-
Example sentences for: cis-
How can you use “cis-” in a sentence? Here are some example sentences to help you improve your vocabulary:
In addition, SRC-3 binding to the heterodimer was decreased by androstanol and this effect was largely blocked by 9-cis-RA.
The interaction of SRC-3 with the preformed and characterized CAR/RXR heterodimer complex was increased by either TCPOBOP or 9-cis-RA (Fig.
We have designed new algorithms for the detection of cis- regulatory modules in the genomes of higher eukaryotes which is a first step in unraveling transcriptional regulatory networks.
Although combinatorial action of transcription factors has been studied throughout the life cycle of organisms [ 2 ] , perhaps the most coherent picture has emerged in the context of developmental processes [ 3 4 ] . Here, a great number of experiments suggest that a major part of the gene regulatory apparatus is organized in the form of separable cis- regulatory modules [ 3 ] . A given module defines specific aspects of the spatio-temporal pattern of gene expression by the combinatorial action of multiple transcription factors which together define the rate of transcription.
The effects of specific RXR ligands on the CAR/RXR heterodimer have not been characterized, although high concentrations of both 9-cis-RA and all-trans retinoic acid have been reported to block PB induction of the CAR targets CYP2B1 and CYP2B2 in primary rat hepatocytes [ 17 ] . In addition, a recent report suggests that both compounds decrease TCPOBOP-dependent CAR transactivation [ 18 ] . In both cases, these effects were primarily attributed to sequestration of limiting amounts of RXR into ligand-dependent homodimers or heterodimers with other receptors.
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