Words similar to cirunt
Example sentences for: cirunt
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Verification of CiRunt was performed by comparing the gDNA to cDNA available on-line at the Nori Satoh Laboratory web page.
Runx1 orthologues contain 3. CiRunt contains 5 exons downstream of the Runt domain, while CeRun contains 4. In vertebrates at least, the multiplicity of downstream exons is reflected in a large variety of alternatively spliced transcripts that give rise to multiple protein isoforms that differ in the C-terminal sequences appended to the Runt domain [ 12 13 ] . It is important to note that the C-terminal exon of all Runx genes identified to date encodes the amino acid sequence VWRPY (or the functionally equivalent IWRPF in the case of C. elegans ), which acts as a recruitment motif for the co-repressor Groucho/TLE [ 3 ] . This motif is at the C-terminus within the 3'-most exon of all of the genes, possibly with the exception of CiRunt (where the open reading frame apparently continues beyond the VWRPY in the genome sequence), and was used in our analysis to identify the C-terminal exons of previously uncharacterised Runx genes.
All of the chordate Runx genes (including CiRunt ) contain an intron within the N-terminal half of the Runt domain, the position of which is invariant with respect to nucleotide sequence.
The C. intestinalis Runx gene ( CiRunt ) was derived from a contig assembled using shot-gun sequence segments queried from NCBI's trace archive.