Words similar to circadian
Example sentences for: circadian
How can you use “circadian” in a sentence? Here are some example sentences to help you improve your vocabulary:
Upon release into constant darkness cry1,2 -/-mice immediately become arrhythmic at the behavioral level [ 22 23 ] , at the level of SCN electrophysiology [ 28 ] , and at the cellular/molecular level [ 23 ] . Of the available mouse models for circadian dysfunction, only per1,2 double mutant mice [ 29 ] , bmal1 knockout mice [ 30 ] , and mice with an ablation of the SCN [ 31 ] show a similarly dramatic phenotype.
If any of these elements are functional, they seem to be for the control of circadian and/or diurnal rhythmicity, light-regulated expression and the binding of Myb-type transcription factors.
The clock mutation in mice, which has a profound effect on circadian rhythmicity [ 33 ] , decreases NREMS time and consolidation under baseline conditions [ 34 ] . The clock sleep phenotype is the inverse of the sleep characteristics we report here for the cry1,2 -/-mice and is thus consistent with CLOCK and CRY1,2 being positive and negative transcriptional regulators, respectively.
Among vertebrates, circadian oscillators have been formally identified in the suprachiasmatic nucleus of the mammalian brain [ 26], the retina [ 27, 28, 29], and the pineal gland of non-mammalian vertebrates [ 30, 31].
Thus, cry1,2 -/-mice appear to be a suitable model for studies of the regulation of sleep in the absence of an intact circadian clock.
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