Example sentences for: chronobiological

How can you use “chronobiological” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Analysis of genetic and molecular mechanisms underlying circadian clocks in whole animals or isolated tissues is facilitated by the use of molecular reporters, such as firefly luciferase ( luc ). The use of firefly- luciferase ( luc ) as a real-time molecular reporter of gene expression has been illustrated in a variety of model systems including cyanobacteria, plants, Drosophila , and mammals [ 15 16 17 18 ] . This method has proved especially valuable in studies about molecular rhythms because real-time expression of clock genes and other chronobiological factors may be monitored over many daily cycles in vivo [ 17 6 19 20 21 ] . Applications of this technique are varied.

  • Previous studies of cryptochrome's chronobiological role in Drosophila emphasized that CRY may function as a deep brain photoreceptor involved in mediating resetting of the clock by light [ 26 ] . Support for this hypothesis came from the observation that locomotor-activity rhythms in cry b flies are unaffected in constant darkness and also maintain rhythmicity under constant light, a condition that causes behavioral arrhythmicity in the wild type [ 33 ] . While antennal rhythms of gene expression and of odor sensitivity in DD are significantly attenuated in cry b tissues ( [ 23 ] , unlike locomotor rhythmicity [ 21 ] ), it remained possible that such effects are due to an altered role of light on the developing clock.


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