Example sentences for: chromosomally

How can you use “chromosomally” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • For such a screen, haploid strains expressing chromosomally integrated GFP fusions to both NIC96 and NUP170 were generated (see Materials and Methods).

  • Among the vast number of animal species that reproduce with males and females, sexual differentiation is controlled either chromosomally or environmentally.

  • In uncloned fibroblast populations, RNA samples from replicate cultures revealed consistent results in comparative large-scale gene expression studies [ 28 ] . Cell lines, i.e. transformed, immortalized or tumor-derived cell lines, are well known to be heteroploid i.e. chromosomally unstable, and any single-cell derived clones of such lines are genetically heterogeneous.

  • S. maltophilia is an important pathogen in nosocomial infections of immunocompromised patients suffering from cancer, cystic fibrosis, drug addition, AIDS and in patients with organ transplants and on dialysis [ 30 31 32 ] . This organism is inherently resistant to most antibiotics due to its low outer membrane permeability [ 33 ] and to β-lactam containing antibiotics due to the production of a chromosomally expressed group 2e β-lactamase (L2) and a group 3c β-lactamase (L1) [ 34 35 ] . L1 has been cloned, over-expressed, and partially characterized by kinetic and crystallographic studies [ 36 37 ] . The enzyme exists as a homotetramer of ca. 118 kDa in solution and in the crystalline state.


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