Words similar to chorionic
Example sentences for: chorionic
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Dual color immunohistochemistry for ERα and ERβ immunoreactivity in chorionic villi (Figure 3)
Binding of truncated USF2 to a HLH element in the prostaglandin G/H synthase 2 (PGHS-2) promoter was abolished in extracts from cells stimulated by human chorionic gonadotrophin (hCG) which signals through cAMP [ 32 ] .
Yet, elevated maternal mid-trimester chorionic gonadotropin is associated with fetal cerebral blood flow redistribution and adverse perinatal outcome [ 63 ] . In addition, estrogens, which are known to cause a diminution of high LH levels in postmenopausal women, have been reported to be effective in the prevention and treatment of Alzheimer's disease [ 72 73 74 ] . Microglia belong among cells of the mononuclear phagocyte system [ 75 ] . Since CG increases secretion of a variety of cytokines by monocytes, and induces their inflammatory reaction and phagocytic activity [ 76 77 78 79 ] , high LH levels in aging individuals may also activate resident macrophages in the central nervous system and contribute to the development of Alzheimer's disease and other inflammation-mediated neurodegenerative diseases.
In normal placentae at term, the LHR immunoreactivity in mature chorionic villi was found in mononucleated cytotrophoblast cells under the syncytial layer (arrowheads, Fig 6A) and villous vascular sinusoids (v), but most of the syncytiotrophoblast was virtually unstained (white asterisks vs. black).
Figure 6Gshows LHR immunostaining of syncytium (black asterisk) and lack of vascular LHR (white arrowhead), resembling immature chorionic villi (immature placental phenotypes, characteristic for intrauterine growth retardation and maternal diabetes [ 52 ] - note lack of dilatation of villous sinusoids).
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