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Example sentences for: chernoff
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As with PrP Sc , yeast prions efficiently recruit soluble molecules of the same species, thus inactivating them (Lindquist 1997; Chernoff 2001; Wickner et al.
The kinase domains of the c-Src Y416F mutant (kind gift of Dr. Joan Brugge, Harvard Medical School, Boston, MA) or the kinase inactive c-Src (K295M, [ 46 ] ), were amplified by PCR and cloned in pJ3H and pJ3M, two vectors for HA- and Myc-tagging at the N-terminus of the protein (kind gifts from Dr. J. Chernoff, Fox Chase Cancer Center, Philadelphia, PA, [ 47 ] ). The pEBG-JNK was a kind gift of Dr. Bruce Mayer (Harvard Medical School, Boston, MA).
The key cellular element that is critical for this process is molecular chaperone Hsp104 (Chernoff et al.