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Example sentences for: chargaff

How can you use “chargaff” in a sentence? Here are some example sentences to help you improve your vocabulary:

Interestingly, the intra-strand Chargaff's rule is violated in a position-dependent manner.
Thus, the twelve possible nucleotide-substitution rates reduce to just six and, at equilibrium, Chargaff's rule should hold even within the set of coding sequences in a genome [ 30].
When Francis worked on the structure of DNA, he had some simple facts, such as Chargaff's Laws, and means to make point mutations from which it could be determined how function followed structure.
They found a unique way to fit the bases in the structure by pairing, and by March 7 they had the double-helix model constructed: it obeyed the Chargaff ratios, it fit the X-ray data for B-DNA, and it provided a rational way to encode and transmit genetic information to subsequent generations.
In actual genomes, however, the intra-strand Chargaff's rule is frequently violated because the leading and lagging strands have different substitution patterns and genes are not evenly distributed [ 31].