Words similar to cerevisiae
Example sentences for: cerevisiae
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Direct biological models of binding-site organization in TCRs, as exemplified by conserved word-pair templates, provided several advantages over naive statistical models based on sequence combinations in S. cerevisiae . Average gene-expression profiles showed that conserved word pairs were more specific predictors of gene expression (giving fewer false positives) than single or pairwise sequences derived from S. cerevisiae , indicating that conserved regions among these closely related Saccharomyces species were enriched for functional sequences.
Yersinia pestis , Pseudomonas aeruginosa , Escherichia coli , and Saccharomyces cerevisiae strains used are listed in Table 3. Y. pestis strains were grown in heart infusion broth or on tryptose blood agar base medium (Difco Laboratories, Detroit, MI) at 26°C for genetic manipulations.
One type of membrane-localization tag is the myristoyl group, which is attached to the glycine residue of proteins, such as S. cerevisiae Gpa1 (the α subunit of the pheromone-responsive G protein) [ 18 ] , that contain at their N-termini the sequence MGXXXS/T (where "X" can be any amino acid) [ 19 ] . Thus, we investigated whether fusion to the sequence MGCTVS, which is present at the N-terminus of Gpa1 and which we will henceforth refer to as "Myr", could restore function to the mutant versions of Boi1 that are impaired in the ability to bind phospholipid.
Database searches of genomic sequences from Saccharomyces cerevisiae (yeast), Caenorhabditis elegans (roundworm), and Strongylocentrotus purpuratus (sea urchin) did not reveal genes encoding the TOX HMG signature sequence (data not shown).
To assess the association between conserved word-pair templates and differentially expressed genes, we identified gene subsets whose TCRs contained both conserved words in the template and observed their expression patterns in S. cerevisiae in publicly available datasets ( [ 30 31 32 33 34 35 ] , see Materials and methods for details).
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