Words similar to cepacia
Example sentences for: cepacia
How can you use “cepacia” in a sentence? Here are some example sentences to help you improve your vocabulary:
B. cepacia LPS and lipid A can help pinpoint the exact structural differences that relate to the relative resistance of B. cepacia to protegrins and to endogenous antimicrobial peptides of humans.
, Burkholderia cepacia , and some strains of Stenotrophomonas maltophilia are usually resistant to colistin [ 8 9 10 11 12 13 14 15 16 17 18 ] . Cross-resistance with other antibiotics has not been reported [ 10 13 ] , and acquired resistance is rare [ 11 17 ] . Although lower susceptibility rates for P. aeruginosa have been reported in patients with cystic fibrosis undergoing chronic prophylactic treatment with inhaled colistin [ 18 ] , 81% of strains of P. aeruginosa from such patients are still susceptible to colistin [ 14 ] .
Incubation of 125I-GGPG with intact P. aeruginosa 9027 (PG-1 sensitive) and B. cepacia 25416 (PG-1 resistant) cells demonstrated a marked difference in protegrin binding between the two strains (Fig.
In our study, LPS and lipid A samples from P. aeruginosa 9027 and B. cepacia 25416 were immobilized on a hydrophobic HPA sensor chip (BR-1000-30, Biacore AB) that was found, in our preliminary experiments, to provide an optimal matrix for LPS and lipid A. The surface of HPA sensor chips is composed of long-chain alkanethiol molecules that form a flat, quasi-crystalline hydrophobic layer that facilitates hydrophobic adsorption of liposomes or micelles on a user-defined polar lipid monolayer.
Our studies demonstrate a correlation between protegrin sensitivity/resistance and protegrin binding in P. aeruginosa and B. cepacia , and support a hypothesis that the relative resistance of B. cepacia to protegrin is due principally to a reduced number of protegrin binding sites on the lipid A moiety of its LPS.
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