Words similar to centroid
Example sentences for: centroid
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The following clustering algorithms were used: seven hierarchical clustering methods (single linkage, average linkage, complete linkage, Ward's minimum variance, density linkage, centroid, and flexible-beta), a k-mean method, and an oblique principle component method employing either (1) Pearson correlation or (2) Spearman correlation based on rank.
Thus, the output of the algorithm is twofold: the method presents a list of the unique centroids identified in the fuzzy clustering cycles along with a matrix representing the final membership scores for each gene to each centroid.
Genes that were correlated to any existing centroid with a Pearson correlation >0.
For example, one centroid (cluster 61, Figure 5aand see [ 14]) represented genes that were strongly repressed in response to prolonged nitrogen starvation but induced by treatment with the sulfhydryl-rearranging drugs dithiothreitol (DTT) and diamide.
Each of the centroid patterns is then recalculated as the weighted mean of all of the gene-expression patterns in the dataset, where each gene's weight is proportionate to its membership in the corresponding cluster (see Materials and methods for details regarding the calculations).
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