Example sentences for: cell-permeable

How can you use “cell-permeable” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • E15 SMG primordia were cultured for 2 days in the presence or absence of the cell-permeable peptide SN50, a potent inhibitor of NF-κB nuclear translocation [ 33 34 35 ] . SN50 is composed of a nuclear localization sequence (NLS) for NF-κB p50 linked to a cell-permeable carrier [ 33 34 35 ] . SN50 blocks the intracellular recognition mechanism for the NLS on NF-κB, thus inhibiting NF-κB's translocation through the nuclear pore.

  • We interrupted the NF-κB signal in embryonic SMG explants using the cell-permeable peptide SN50, a potent inhibitor of NF-κB nuclear translocation [ 25 26 ] , [ 33 34 35 ] . SN50-mediated inhibition of NF-κB nuclear translocation in SMG explants results in extensive apoptosis and a very substantial decline in cell proliferation.

  • Moreover, treatment of the macrophages with SN50, a cell-permeable peptide that specifically prevents activation of NF-κB by inhibiting its nuclear translocation [34], nearly abolished endotoxin-induced activation of resistin expression (Figure 4D).

  • Cells were stained 10-20 minutes with 5 μg/ml of the cell-permeable DNA binding dye Hoechst 33342.


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