Words similar to cddo

Example sentences for: cddo

How can you use “cddo” in a sentence? Here are some example sentences to help you improve your vocabulary:

In addition, significant inhibition of MMP-13 did not require the pretreatment of cells with CDDO.
In all cell types, CDDO inhibited the IL-1-induced expression of MMP-13 mRNA more effectively than that of MMP-1.
Furthermore, with the use of SW-1353 cells stably transfected with a Bcl-3 expression plasmid, Bcl-3 could sustain the expression of MMP-1, but not that of MMP-13, against inhibition by CDDO.
We found that CDDO inhibited the expression of these enzymes in a chondrocyte cell line, human primary chondrocytes and synovial fibroblasts.
Naturally occurring triterpenoids, such as ursolic acid, have been found to have mild anti-inflammatory effects [ 18 27 ] . These have been improved with the development of synthetic triterpenoids such as CDDO, offering a potential therapeutic tool for the treatment of arthritis and other diseases [ 19 20 21 ] . Furthermore, it has been reported that CDDO at high doses (5-10 μM) can have pro-apoptotic effects, ideal for the treatment of leukemia but of concern with regard to chondrocyte cell death [ 25 26 ] . However, we found that CDDO, at concentrations that decrease MMP-1 and MMP-13 expression (namely 300 nM and 1 μM), did not cause cell death.