Words similar to catalase
Example sentences for: catalase
How can you use “catalase” in a sentence? Here are some example sentences to help you improve your vocabulary:
This protective mechanism declines with age because a study analyzing metallothionein levels in RPE of macular region showed a dramatic decrease in aged donors (mean age = 80-yr) as compared to those from younger donors (mean age = 58-yr) [ 36 ] . A separate report concluded that there was also an age-dependent decrease of catalase activity in RPE [ 37 ] . These studies suggest RPE in the elderly are more susceptible to oxidative stress induced damage, which may contribute to age-related RPE dysfunction and vision loss.
Altered placental vascular dynamics and shifts in fetal organ blood flow precipitated by nutrient deficiencies are of possible significance [ 35 ] . Ischemia-reperfusion is a well known stimulus of free radical formation [ 36 ] . Micronutrient imbalances or insufficiencies also can negatively impact the functional capacities of antioxidant vitamin (C, E) and enzymatic (superoxide dismutase, glutathione peroxidase, catalase) defense systems [ 37 ] .
Disulfide bond formation is associated with a conformational change that alters OxyR binding to DNA and allows the protein to activate the transcription of genes encoding enzymes, such as catalase and the alkylhydroperoxide reductase, that destroy H 2 O 2 . Once the H 2 O 2 concentration is decreased, OxyR is reduced and the system is reset.
An increase of oxidative stress in RPE is associated with an increase of cellular catalase, metallothionein [ 3 ] and glutathione S-transferase [ 35 ] , which should serve as a protective mechanism to decrease the cytotoxicity caused by H 2 O 2 and other reactive oxygen species.
Abundant catalase enzyme then converts the hydrogen peroxide into molecular oxygen and water.
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