Words similar to catalase
Example sentences for: catalase
How can you use “catalase” in a sentence? Here are some example sentences to help you improve your vocabulary:
Altered placental vascular dynamics and shifts in fetal organ blood flow precipitated by nutrient deficiencies are of possible significance [ 35 ] . Ischemia-reperfusion is a well known stimulus of free radical formation [ 36 ] . Micronutrient imbalances or insufficiencies also can negatively impact the functional capacities of antioxidant vitamin (C, E) and enzymatic (superoxide dismutase, glutathione peroxidase, catalase) defense systems [ 37 ] .
As iron accumulates, it competes with catalase for hydrogen peroxide and forms hydroxyl radicals (Fe 2++ H 2 O 2 → Fe 3++ OH -+ OH ·) - so-called reactive oxygen species that can attack mtDNA, membrane lipids, carbohydrates and proteins.
An increase of oxidative stress in RPE is associated with an increase of cellular catalase, metallothionein [ 3 ] and glutathione S-transferase [ 35 ] , which should serve as a protective mechanism to decrease the cytotoxicity caused by H 2 O 2 and other reactive oxygen species.
This protective mechanism declines with age because a study analyzing metallothionein levels in RPE of macular region showed a dramatic decrease in aged donors (mean age = 80-yr) as compared to those from younger donors (mean age = 58-yr) [ 36 ] . A separate report concluded that there was also an age-dependent decrease of catalase activity in RPE [ 37 ] . These studies suggest RPE in the elderly are more susceptible to oxidative stress induced damage, which may contribute to age-related RPE dysfunction and vision loss.
To determine the effect of consumption of FOC on endogenous antioxidant enzyme activity, the activities of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX) were determined in the liver, colon and tumor of mice that had consumed the diet for two weeks.
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