Example sentences for: catabolism

How can you use “catabolism” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Human Fhit [ 14 ] and the S. cerevisiae Fhit homolog [ 13 ] , which was called Aph1 but is here termed Hnt2 under nomenclature aproved by the Saccharomyces Genome Database, cleave ApppA more readily while Aph1, the S. pombe homolog, cleaves AppppA more readily [ 20 ] . Consistent with the ApppA hydrolase activity of purified Fhit protein, most cancer cell lines that are Fhit negative at the protein level have higher levels of ApppA than cell lines that are Fhit positive [ 21 ] . Nonetheless, the actual concentrations of dinucleoside polyphosphates were submicromolar in every cell culture sample [ 21 ] and thus, under the reported culture conditions, the measured dinucleoside polyphosphates would not be expected to occupy the Fhit active site substantially [ 19 ] . Dinucleoside polyphosphate levels were measured in adenine-requiring S. cerevisiae strains before or after disruption of the Fhit-homologous HNT2 gene [ 13 ] and in adenine-requiring S. pombe strains as a function of disruption and overexpression of the Fhit-homologous aph1 gene [ 22 ] . Recently, it was observed that diadenosine polyphosphates undergo a divalent cation-dependent conformational change that might mediate their biosynthesis, catabolism or signaling properties [ 23 ] .

  • The lysosome is a pivotal organelle responsible for a diverse spectrum of cellular functions including protein and lipid catabolism, vesicular transport and sorting [ 1 ] . Abnormal lysosomal physiology may result in cellular dysfunction, and eventually lead to a variety of diseases.

  • 2-Amino-3-carboxymuconate semialdehyde can be considered to be a branchpoint metabolite that either enters committed catabolism to acetyl-CoA or that enters biosynthesis to NAD +/NADP +. In the central nervous system, a number of kynurenine-pathway metabolites are neuroactive and appear to be involved in inflammatory neurological diseases [ 32].

  • Thus, tryptophan catabolism exerts control over fundamental cellular functions.

  • Uptake is defined as the net difference between tocopherol transported into the cells and loss due to catabolism and/or in vitro oxidation.


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