Words similar to cas

Example sentences for: cas

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To determine if the tyrosine-phosphorylated Cas SD chimera affected other signaling pathways, we tested whether the association between c-crk and C3G was affected in NIH3T3 cells expressing the chimera (Fig.
These data suggest that the tyrosine phosphorylated Cas chimera perturbs signaling via v-crk and probably via endogenous c-crk to affect the activation of the JNK pathway.
JNK was immunoprecipitated and tested for activity from control NIH3T3 cells, those expressing the Cas chimera and those expressing the Cas chimera and v-crk (Fig.
However, we found that placing the Cas SD at the N-terminus of the Src kinase domain was inferior to placing it at the C-terminus with regards to tyrosine phosphorylation of the Cas SD.
Such a mutant is inactive against exogenous substrates [ 34 35 36 ] . We found that this Src*/Cas(SD) molecule is constitutively tyrosine phosphorylated when expressed either transiently or stably in cells, and acts as a dominant negative mutant, attenuating v-crk mediated transformation when expressed in cells transformed by this oncogene.