Example sentences for: cas

How can you use “cas” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Thus while both sets of motifs in the Cas SD have been thought to interact with the v-crk SH2 domain, we demonstrated that this domain only interacts with the YDXP motifs.

  • Investigators have shown that v-crk interacts via its SH2 domain with the substrate domain of Cas [ 6 ] . Association of v-crk with endogenous Cas is believed to protect the phosphorylation status of this molecule due to protection from phosphatases [ 12 ] . Expression of an unphosphorylated Cas SD along with v-crk should therefore result in stable tyrosine phosphorylation of the Cas SD if they interact.

  • Suppression of v-crk mediated transformation by tyrosine phosphorylated Cas SD

  • To determine if the tyrosine phosphorylated chimera could compete with endogenous Cas for binding to endogenous c-crk, we transfected either the isolated attenuated Src kinase domain as control, or the tyrosine phosphorylated Cas substrate domain (Src*/Cas(SD)) into Cos-7 cells, and immunoprecipitated endogenous c-crk (Fig.

  • By contrast, co-expression of v-crk with the chimera resulted in reduction in the association of v-crk with endogenous Cas and in induced association of v-crk with the tyrosine phosphorylated Cas 3'SD (Fig.


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