Words similar to cas
Example sentences for: cas
How can you use “cas” in a sentence? Here are some example sentences to help you improve your vocabulary:
The JNK pathway is regulated by interaction of c- or v-crk with Cas via the substrate domain [ 38 ] . In determining which pathways are affected in our stable cell lines generated, we determined if JNK was activated in the v-crk transformed cells, and if the tyrosine phosphorylated Cas chimera was affecting this activation.
Our initial experiments were designed to determine whether tyrosine phosphorylation of the SD of Cas would lead to the assembly of protein complexes and activation of downstream effectors.
In particular, we found that the tyrosine phosphorylated Cas SD domain blocked v-crk mediated activation of the JNK pathway.
We therefore used these fusions to determine which region of the Cas SD interacts with v-crk.
Figure 5ademonstrates that stable expression of the Src*/Cas(SD) chimera resulted in constitutive tyrosine phosphorylation of this protein in NIH3T3 cells.