Words similar to carvedilol
Example sentences for: carvedilol
How can you use “carvedilol” in a sentence? Here are some example sentences to help you improve your vocabulary:
They reported levels of apoptotic cells for control andNYHA III-IV hearts that were similar to our observations [ 35 ] . We similarly believe that the suppressionof apoptosis by carvedilol is likely due to its antioxidative propertiesrather than the β-blocking effects [ 35 ] . Webase this on our observation that a similar reduction in the incidenceof apoptosis was seen at both a non-pharmacological (no effect onheart rate or blood pressure) as well as a pharmacological doseof carvedilol.
Thiseffect was independent of heart rate lowering effects, i.e. β-blockade.The beneficial effects of carvedilol can therefore be obtained withsubtherapeutic doses.
In a canine model of chronic heart failure producedby multiple sequential intracoronary embolizations, metprolol, a β 1 selectiveblocker, reduced the incidence of apoptosis supporting our experimentalobservations with carvedilol [ 36 ] .The incidence of apoptosis was 5.32 ± 0.77 in heart failure animalsthat were not treated which is similar to our findings of 5.64 ±0.
Effect of Carvedilol on Ventricular Function
This is a novel observation and importantin treating patients who may not tolerate higher doses (heart rateand blood pressure lowering) of carvedilol.
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