Example sentences for: cardiolipin

How can you use “cardiolipin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The loss of cytochrome c causes a break in the electron transfer chain resulting in the production of reactive oxygen species [ 31 ] . Reactive oxygen species are known to cause the oxidation and loss of function of many lipids including cardiolipin [ 20 ] . Finally, caspases activated downstream of cytochrome c release have been implicated in mitochondrial damage [ 29 ] . It appears likely that the cumulative damage of these agents could lead to the irreversible loss of mitochondrial membrane integrity and structure.

  • The presence of cardiolipin has been implicated in the function of numerous mitochondrial proteins including, sites I and III of the electron transport chain, the adenine nucleotide transporter, the protein translocation machinery, and the localization of mitochondrial creatine kinase [ 19 20 21 22 ] .

  • This distinction suggests that tBid might localize to contact sites because of the arrangement of cardiolipin there.

  • Cardiolipin is present at much lower concentrations elsewhere in the outer membrane.

  • As previously noted, contact sites are purported to have a unique lipid environment that is rich in cardiolipin.


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