Words similar to cardiolipin
Example sentences for: cardiolipin
How can you use “cardiolipin” in a sentence? Here are some example sentences to help you improve your vocabulary:
The presence of cardiolipin has been implicated in the function of numerous mitochondrial proteins including, sites I and III of the electron transport chain, the adenine nucleotide transporter, the protein translocation machinery, and the localization of mitochondrial creatine kinase [ 19 20 21 22 ] .
This distinction suggests that tBid might localize to contact sites because of the arrangement of cardiolipin there.
Indeed it was found that the targeting of tBid to mitochondria-like membranes occurs in the absence of proteins, yet depends upon cardiolipin being in a possibly unique structure as opposed to free cardiolipin [ 9 ] . The requirement for a specific cardiolipin structure that is likely defined by the contact site is consistent with our observation that no gold particles were found in regions stripped of the outer membrane exposing the cardiolipin-rich inner membrane.
For example, there was consistently more AA accumulating in various hepatic PL than in the hippocampus following AA feeding; and more DHA accumulated in hepatic cardiolipin (CL) than in hippocampal CL, whereas the reverse was true for phosphatidylserine/phosphatidylinositol (PS/PI).
The loss of cytochrome c causes a break in the electron transfer chain resulting in the production of reactive oxygen species [ 31 ] . Reactive oxygen species are known to cause the oxidation and loss of function of many lipids including cardiolipin [ 20 ] . Finally, caspases activated downstream of cytochrome c release have been implicated in mitochondrial damage [ 29 ] . It appears likely that the cumulative damage of these agents could lead to the irreversible loss of mitochondrial membrane integrity and structure.
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