Words similar to caldesmon
Example sentences for: caldesmon
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The high molecular weight caldesmon (h-caldesmon) is the major isoform of intact vascular smooth muscle [ 7 ] . On the Western blots h-caldesmon appeared as a single band with apparent molecular weight of 130 kDa, which comigrated with h-caldesmon standard, purified from porcine stomach [ 8 ] . Densitometry of immunoreactive bands revealed that the artery contained approximately 1.39 times more h-caldesmon than vein (Fig.
Screening of the translated non-redundant database at GenBank with the amino acid sequence of the yeast D/E-rich domain selected numerous other aspartate-glutamate rich proteins, including neurofilament proteins and caldesmon.
Differences in the content of caldesmon, or the TM isoforms, therefore, might be associated with modulatory effects on the time profile or magnitude of contraction.
Moreover, it has been recognized that caldesmon and TM can modulate the actin-myosin interaction in a cooperative manner [ 20 ] , suggesting that functional effects of these proteins on actin-myosin coupling and smooth muscle mechanics ought to be interpreted in parallel.
The tissue homogenization conditions [ 1 ] favor extraction of the major smooth muscle cell contractile proteins actin and myosin, and the thin filament-binding components caldesmon, calponin, and tropomyosin (TM).
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