Words similar to caldesmon

Example sentences for: caldesmon

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The high molecular weight caldesmon (h-caldesmon) is the major isoform of intact vascular smooth muscle [ 7 ] . On the Western blots h-caldesmon appeared as a single band with apparent molecular weight of 130 kDa, which comigrated with h-caldesmon standard, purified from porcine stomach [ 8 ] . Densitometry of immunoreactive bands revealed that the artery contained approximately 1.39 times more h-caldesmon than vein (Fig.
There were significant differences in the content of caldesmon.
Moreover, it has been recognized that caldesmon and TM can modulate the actin-myosin interaction in a cooperative manner [ 20 ] , suggesting that functional effects of these proteins on actin-myosin coupling and smooth muscle mechanics ought to be interpreted in parallel.
We assayed the contents of some thin filament binding proteins, proposed to play roles in modulation of the actin-myosin coupling, e.g. calponin, caldesmon, and TM.
Caldesmon is likely to play a modulatory role on the production of smooth muscle force via a tethering of actin to myosin [ 11 ] and/or of its effects on the actomyosin ATPase [ 12 13 14 ] . Similarly, TM does not seem to function as a major regulatory protein, but modulatory effects due to its ability to maintain the actin filamentous structure [ 15 ] , to inhibit the Ca 2+-ATPase activity [ 16 ] , alter the cytoskeletal dynamics [ 17 ] and improve actin filament flexibility during the contraction/relaxation cycle [ 18 19 ] have been well documented.