Example sentences for: cadherin

How can you use “cadherin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Both cell adhesion and connective tissue remodeling are indispensable for normal development and maintenance of tissue integrity [ 13 14 15 ] . The differential expression of proteoglycans, collagens and cell adhesion molecules (for example cadherin 13) might be involved in genital morphogenesis and later stability of sexually dimorphic traits of the external genitalia.

  • Hybrid toxin 4109 is particular useful in this context, because it is comprised of domains I and II from Cry1Aa and domain III from Cry1Ac (Aa/Aa/Ac) [ 3 ] . Hybrid-toxin 4109 binding to both receptors was not noticeably different from Cry1Aa: for APN binding, k a = 1.9 × 10 4M -1s -1(+/- 1.4 × 10 2), k d = 1.5 × 10 -3s -1(+/- 1.6 × 10 -5), and K D = 78 nM; for cadherin binding, k a = 1.3 × 10 4M -1s -1(+/- 2 × 10 2), k d = 3.34 × 10 -5s -1(+/- 2 × 10 -5), and K D = 2.6 nM.

  • The cadherin off-rate observed in this study could have significant consequences in vivo: slow toxin dissociation may enable protracted lingering near the brush border membrane surface, greatly facilitating toxic (domain I) insertion and subsequent pore formation.

  • However, our immunohistochemical analysis of E-cadherin protein showed no evidence of decreased expression in precursor CIN lesions.

  • , head poly(A)+ RNA from fly heads that expressed dominant-negative Fos and Jun molecules; and poly(A)+ RNA from HEK293 cells that expressed either a cadherin or Tcf inhibitor of the β-catenin pathway were also collected and examined [ [ 7 8 ] ; Kamb, unpublished].


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