Words similar to cadherin
Example sentences for: cadherin
How can you use “cadherin” in a sentence? Here are some example sentences to help you improve your vocabulary:
The genes CA 9 ( carbonic anhydrase IX ), CCND1 ( cyclin D1 ), CDH2 ( N-Cadherin ), EGFR ( epidermal growth factor receptor ) and TGFA ( tranforming growth factor alpha ) all showed increases in CC expression that matched the literature and had p-values ≤ 0.0061 [ 11 12 13 14 15 ] . The observed decrease in CDH1 ( E-cadherin ) in CC (p-value = 0.0045) also matched previously published reports, as did the decrease in VIM ( vimentin ) expression in Chr RCCa [ 13 16 ] . VIM was also found to be increased in CC with a p-value = 0.0045, which was consistent with the literature.
Hybrid toxin 4109 is particular useful in this context, because it is comprised of domains I and II from Cry1Aa and domain III from Cry1Ac (Aa/Aa/Ac) [ 3 ] . Hybrid-toxin 4109 binding to both receptors was not noticeably different from Cry1Aa: for APN binding, k a = 1.9 × 10 4M -1s -1(+/- 1.4 × 10 2), k d = 1.5 × 10 -3s -1(+/- 1.6 × 10 -5), and K D = 78 nM; for cadherin binding, k a = 1.3 × 10 4M -1s -1(+/- 2 × 10 2), k d = 3.34 × 10 -5s -1(+/- 2 × 10 -5), and K D = 2.6 nM.
Dong and co-workers have shown earlier that the CDH1 promoter is methylated in 28% of invasive CC [ 13 ] . E-cadherin, CDH1 , is a major adhesion component of epithelial cells, which plays an important role as an invasion suppressor gene.
Tumors were considered positive for E-cadherin when cells showed membrane staining.
Binding studies indicated that the affinity of the cadherin for Cry1Aa is equivalent to that of the brush border membrane vesicles from B. mori [ 16 ] , an affinity that is substantially lower than the APN affinities reported.
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