Words similar to cachexia
Example sentences for: cachexia
How can you use “cachexia” in a sentence? Here are some example sentences to help you improve your vocabulary:
Moreover, the wasting, weight loss, and cachexia associated with AIDS has also been related to TNF-α activity [ 42 ] . Thus both IFN-γ and TNF-α have the potential for a double role in the pathogenesis associated with AIDS i.e. antiviral and inflammatory responses.
TTP-deficient mice exhibit cachexia, with dermatitis, medullary and extramedullary hyperplasia, erosive polyarthritis, and autoimmunity with autoantibodies [ 25 ] . This phenotype is similar to that observed in mice that overexpress TNF [ 26 ] . In agreement with these data, TTP-deficient mice were shown to overproduce TNF, and weekly injections of a neutralizing antibody to TNF eliminated the predominant features of this phenotype.
The significantly higher body weight gain is likely due to reduced tumor related cachexia.
These findings assume clinical importance since they may explain in part the chronic and autoimmune pathologies in the elderly, particularly rheumatoid arthritis, Crohn's disease, sepsis, and myelodysplastic syndromes, which are exacerbated by the inflammatory cytokines IFN-γ and TNF-α [ 41 ] . Likewise, the elevation of these cytokines, particularly TNF-α potentially may contribute to the deterioration in the HIV +or AIDS patient by promoting wasting and cachexia [ 42 ] .
It has been reported that omega 3 fatty acids can decrease tumor cachexia [ 19 20 21 ] . It is important to note that tumor bearing mice that received only 3% FOC in their diet gained more weight prior to initiation of DOX therapy than mice that did not receive FOC.
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