Words similar to burden

Example sentences for: burden

How can you use “burden” in a sentence? Here are some example sentences to help you improve your vocabulary:

Significant reductions in total dose and dose intensity have an adverse effect on disease-free survival and overall survival [ 9 10 ] . Because most dose delays and reductions occur after a neutropenic complication or febrile neutropenia, patients might experience an infectious episode and might need to contend with the burden and anxiety associated with a hospitalization and the risk of prolonged complications in treatment.
Additional material was not requested, since this would have posed an undue burden on the clinical site staff and would have risked raising questions about emerging differences among treatment groups.
One reason for this disappointing stoicism may be that for the middle class the tax burden isn't in fact rising.
Where should the burden of proof fall?
The article does an excellent job of describing the potential burden of China's size: "With a population of 1.3 billion that expands at 1% a year, the country must add at least 7.5 million jobs a year just to absorb the people entering the labor force," it explains.