Words similar to burden

Example sentences for: burden

How can you use “burden” in a sentence? Here are some example sentences to help you improve your vocabulary:

The information collections associated with the final rule contain 3,527,901 burden hours which include 1,433,579 burden hours for a one time start up expenditure for 7,237 manufacturers and 2,094,321 burden hours expended annually by 7,237 manufacturers.
Because splenocyte transfer alone had resulted in no significant reduction in tumor burden, this group was not tested for survival benefit, for logistical reasons.
If a woman knows she is going to get some help that will be a burden off her mind, if the law will help her keep that person away from her."
Where possible, the underlying cause should be treated to at least provide symptomatic relief when the burden of the therapy does not outweigh the benefit.
In our experience of working with people with HIV in Africa, the result of this burden is often a downward spiral marked by fatalism, self-loathing, and isolation from others.