Example sentences for: brn

How can you use “brn” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Moreover, recent work shows that in embryos NT-3 is primarily expressed in supporting cells, moving only around birth into hair cells [ 6 7 ] . In fact, the selective loss of vestibular as compared to cochlear sensory neurons (77% versus 29%; [ 3 ] ) suggests that NT-3 expression may be less downregulated in Brn3c null mutants than BDNF [ 6 8 9 ] , provided that at least some differentiation of supporting cells takes place.

  • Cochleotopic projection was evaluated by inserting DiI soaked filter strips into the base and DiA soaked filter strips into the apical turn of 2 P0 and 4 P8 Brn3c null mutants and a similar number of wildtype littermates.

  • The progressive loss of afferent and efferent innervation in Brn3c null mutants shows neither in spatial nor in temporal pattern a resemblance to losses reported in simple BDNF or NT-3 null mutations [ 6 ] . Null mutants of ear specific neurotrophins have completed the loss of sensory neurons before birth.

  • The BDNF signal in the utricle was clearly centered on the hair cells in the control animal but some aggregation of silver grains appeared also in the Brn3c null mutants (data not shown).

  • In control animals there is dense innervation of inner hair cells, whereas Brn3c null mutants show a curious aggregation of fibers near focal spots around the habenula perforata.


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