Example sentences for: breakage

How can you use “breakage” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Background breaks at any site in the region contribute to noise, therefore the background breakage at any given site is apparently less than one in 30,000.

  • A simplest interpretation of our data is that RecBCD enzyme is involved in repair and degradation of broken chromosomes, and that RecA, RecFOR, RecQJ and RecET functions are involved in prevention and/or repair of the breakage.

  • We proposed that this nested set is generated by alternative breakage patterns of polytene chromatids of the 81 locus DNA ( [ 27 ] ; bottom, Fig.

  • Although chromatid breakage requires an endonuclease activity, the cutter, directed by a Cbs-binding activity, no Cbs-dependent "binder/cutter" activity has been detected in vitro . The cutter could be an activity of telomerase itself [ 39 43 ] . Telomerase of both Tetrahymena and Euplotes has a single-strand endonuclease activity [ 45 43 ] . It can trim potential primers back, so that the 3' terminus pairs with template RNA [ 46 ] . Thus, while it may serve a 3' editing function, the existence of a nuclease activity in potential proximity to the site of chromatid breakage is provocative, suggesting that telomerase provides the

  • The first model is what we take to be the accepted model in the field for chromatid breakage and telomere formation at a single TAS, and what we propose also to be the mechanism operating at the arm-distal single-TAS regions.


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