Words similar to brainstem
Example sentences for: brainstem
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However, for example, we found NK-ir structures (the antibody used in this study principally recognizes NKA)(see specificity of the antiserum in Methods) in the human brainstem in the lateral cuneate nucleus and in the pyramidal tract, in which no SP-ir structure has been described in humans [ 24 25 26 27 ] . It is known that both neuropeptides, SP and NKA, are derived from the same precursor.
Our data are in agreement with previous results described in the rat brainstem, using radioimmunoassay techniques [ 29 30 ] . Thus, these latter authors found higher levels of NKA and lower levels of NKB in both the midbrain and the medulla oblongata of the rat [ 30 ] . In both regions of the human brainstem, we observed a high density of NK-ir structures.
Thus, the differences found in the distribution of both neuroactive substances in the human brainstem could be due to the intraneuronal segregation transport of the peptides and/or the different processing of the precursor [see [ 31 ] ]. Another possibility could be that the immunoreactivity observed in those nuclei of the human brainstem in which NK-ir structures, but not SP, are found is due to NKB (the antibody used here also recognizes NKB).
Possible physiological actions of the NK in the human brainstem
DiI tracing from the brainstem was performed as previously described [ 41 ] . Small filter stripes soaked with saturated DiI were implanted into the efferent fiber bundle near the floor plate or into the ascending or descending afferents in the alar plate [ 42 ] . After appropriate diffusion time of the dye, the ears were dissected and mounted flat for visualization in an epifluorescent microscope.
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