Words similar to bpti
Example sentences for: bpti
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Systemic and local delivery of an adenovirus encoding ATF have been shown to inhibit the growth of primary tumour implants as well as of tumour metastasis in different animal models [ 18 19 ] . In the ATF-BPTI chimeric protein, ATF has two functions (1) the anti uPA effect with its known angiostatic activity and (2) delivery of BPTI at the tumour site due to over-expression of uPAR on tumour and endothelial cells.
BPTI: Bovine Pancreatic Trypsin Inhibitor
BPTI: Bovine Pancreatic Trypsine Inhibitor
An mhATF-BPTI ELISA was developed by P. Quax et al [ 21 ] , using a monoclonal antibody specific for the ATF as the capture antibody and a polyclonal antibody directed against BPTI as the detector antibody.
The murinised version of ATF-BPTI differs by four amino acids from the human version It was shown to bind to the rat receptor and to inhibit plasmin activity in a rat model [ 21 ] . BPTI (commercialised as aprotinin) is a serine protease inhibitor prepared from bovine lung tissue which dose dependently inhibits human trypsin, plasmin and kallikrein.