Example sentences for: bpti

How can you use “bpti” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • (TNO-Prevention and Health, Leiden The Netherlands), using a monoclonal antibody specific for the ATF as the capture antibody and a polyclonal antibody directed against BPTI as the detector antibody [ 24 ] . As a standard we used either urokinase or mhATF-BPTI.

  • BPTI: Bovine Pancreatic Trypsine Inhibitor

  • BPTI: Bovine Pancreatic Trypsin Inhibitor

  • Systemic and local delivery of an adenovirus encoding ATF have been shown to inhibit the growth of primary tumour implants as well as of tumour metastasis in different animal models [ 18 19 ] . In the ATF-BPTI chimeric protein, ATF has two functions (1) the anti uPA effect with its known angiostatic activity and (2) delivery of BPTI at the tumour site due to over-expression of uPAR on tumour and endothelial cells.

  • BPTI has been used systemically in a few animal tumour models, and showed anti-tumour effects in a mouse hepatoma, lung carcinoma, and mammary carcinoma [ 22 23 24 ] , and in a fibrosarcoma of the hamster [ 24 ] . However, BPTI was not further developed as a systemic anti tumour agent probably because of its anti fibrinolytic property that might preclude its use in cancer patients.


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