Words similar to bone-resorbing

Example sentences for: bone-resorbing

How can you use “bone-resorbing” in a sentence? Here are some example sentences to help you improve your vocabulary:

Osteoclasts are large, multinucleated bone-resorbing cells derived from the monocyte-macrophage lineage [ 1 ] . Their bone-resorbing capacity is unique; no other cell shares this capability.
The two major components of the staphylococcal cell wall, peptidoglycan and lipoteichoic acid have been reported to produce inflammation [ 51 52 ] and specifically to induce arthritis [ 53 ] . Bacterial peptidoglycan is also known to stimulate the bone-resorbing activity of macrophages [ 54 ] . Furthermore, staphylococci produce an array of secreted products capable of inducing or sustaining inflammation.
Once in the tissue, monocytes undergo the poorly understood process of transformation to macrophages with altered morphology and function [ 19 ] . In arthritis, synovial macrophages might cause joint destruction by differentiating to bone-resorbing osteoclasts [ 20 ] or by releasing cartilage-degrading enzymes and cytokines, such as interleukin-1 and tumor necrosis factor-α [ 8 ] . It has therefore been suggested that therapies for chronic arthritis should be aimed at depleting joint mononuclear cells or controlling the activation of synovial macrophages [ 21 ] . Indeed, elimination of macrophages by clodronate-laden liposomes in rat models of adjuvant [ 22 ] and antigen-induced arthritis [ 23 ] induces amelioration of the arthritis.