Words similar to bone-resorbing

Example sentences for: bone-resorbing

How can you use “bone-resorbing” in a sentence? Here are some example sentences to help you improve your vocabulary:

Osteoclasts are large, multinucleated bone-resorbing cells derived from the monocyte-macrophage lineage [ 1 ] . Their bone-resorbing capacity is unique; no other cell shares this capability.
Once in the tissue, monocytes undergo the poorly understood process of transformation to macrophages with altered morphology and function [ 19 ] . In arthritis, synovial macrophages might cause joint destruction by differentiating to bone-resorbing osteoclasts [ 20 ] or by releasing cartilage-degrading enzymes and cytokines, such as interleukin-1 and tumor necrosis factor-α [ 8 ] . It has therefore been suggested that therapies for chronic arthritis should be aimed at depleting joint mononuclear cells or controlling the activation of synovial macrophages [ 21 ] . Indeed, elimination of macrophages by clodronate-laden liposomes in rat models of adjuvant [ 22 ] and antigen-induced arthritis [ 23 ] induces amelioration of the arthritis.
The two major components of the staphylococcal cell wall, peptidoglycan and lipoteichoic acid have been reported to produce inflammation [ 51 52 ] and specifically to induce arthritis [ 53 ] . Bacterial peptidoglycan is also known to stimulate the bone-resorbing activity of macrophages [ 54 ] . Furthermore, staphylococci produce an array of secreted products capable of inducing or sustaining inflammation.