Words similar to bmp-induced
Example sentences for: bmp-induced
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The proteasome specific inhibitor lactacystin also inhibited the BMP-induced GAL4-Smad1 transcriptional activity (Fig.
Thus, SNIP1 is an inhibitor of BMP-induced gene response.
However, when the time courses of Wnt- and BMP-induced gene expression were compared, it appeared that BMP-4 acts as soon as at 30 minutes, but that Wnt takes 2 hours to have an effect (Figure 3).
This data further suggests that the inhibitory activity of SNIP1 is mediated by its interaction with CBP/p300, similar to what has been reported in the TGF-β pathways [ 25 ] . We next tested the inhibitory activity of SNIP1 on the transcriptional activity of Smad1, using the GAL4-Smad1 and GAL4-Luc reporter system, as described previously [ 42 43 ] . SNIP1 inhibited BMP-induced activation of GAL4-Luc in p19 cells transfected with GAL4-Smad1 (Fig.
The molecular mechanism(s) of BMP-induced dendritic growth downstream of Smad-1 activation are not well characterized.