Words similar to bmal

Example sentences for: bmal

How can you use “bmal” in a sentence? Here are some example sentences to help you improve your vocabulary:

At least 90 genes are regulated in a similar fashion by NPAS2:BMAL1 [ 37 ] and the identity of the target genes critical for the NREMS phenotype in cry1,2 -/- mice remains to be determined.
For five other targets ( bmal1 , clock , npas2 , per3 , and csnk1e ), expression was quantified in the cortex only.
Recently, the search for components of the vertebrate circadian system has led to the identification of homologues of period [ 6, 7, 8, 9, 10, 11, 12] and timeless [ 13, 14, 15, 16], originally characterized as central clock genes in Drosophila , as well as Clock and Bmal1 ( Cycle ), identified initially in the mouse [ 17, 18, 19, 20, 21].
In mammals, the positive elements are two basic helix-loop-helix (bHLH) PAS-domain-containing transcription factors, CLOCK and BMAL1, that form heterodimers that can drive the transcription of three period ( per ) genes per1-3 and two cryptochromes ( cry1,2 ). PER1,2 and CRY1,2 proteins suppress CLOCK:BMAL1-mediated transcription thereby forming the negative elements in the feedback loop.
Albumin D-binding protein ( Dbp ) is a transcription factor whose expression is under the direct transcriptional control of CLOCK:BMAL1 [ 26 ] . Deletion of the dbp gene, which results in a shortening of the circadian period [ 35 ] , also results in decreased sleep consolidation and NREMS delta power [ 36 ] .