Words similar to bmal

Example sentences for: bmal

How can you use “bmal” in a sentence? Here are some example sentences to help you improve your vocabulary:

At least 90 genes are regulated in a similar fashion by NPAS2:BMAL1 [ 37 ] and the identity of the target genes critical for the NREMS phenotype in cry1,2 -/- mice remains to be determined.
In the discussion, we have focused on per1,2 mRNAs as transcriptional targets of cry1,2 because the expression patterns of these circadian genes have been widely described and because their transcriptional control by CRY proteins and by CLOCK/NPAS2:BMAL1 has been well established.
A recent study in Drosophila melanogaster implicates transcriptional regulation by the circadian gene cycle , a homolog of the mammalian bmal1 gene, in the homeostatic regulation of rest [ 16 ] . While rest in flies shares several features with sleep in mammals [ 17 18 ] , it remains to be determined whether a similar role for BMAL1 or related transcriptional regulators is necessary for the homeostatic regulation of sleep.
Upon release into constant darkness cry1,2 -/-mice immediately become arrhythmic at the behavioral level [ 22 23 ] , at the level of SCN electrophysiology [ 28 ] , and at the cellular/molecular level [ 23 ] . Of the available mouse models for circadian dysfunction, only per1,2 double mutant mice [ 29 ] , bmal1 knockout mice [ 30 ] , and mice with an ablation of the SCN [ 31 ] show a similarly dramatic phenotype.