Example sentences for: biophores

How can you use “biophores” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We therefore designed some potential drug by grouping several biophores into a single molecule, thereby creating a single molecule cocktail of drug activity.

  • Based on the biophores that were identified by the program, a generic structure of the DA agonist was constructed (Figure 4).

  • Analysis of biophores #1, #2 (#4, #5) showed that both of them occur in substituted 5-[4-(benzyloxy) phenyl]-1,3,4-oxadiazol-2-(3H)-ones and their analogs (Figure 1), many of which are known to be strong MAO-B inhibitors [ 9 ] . Biophore #2 represents a flexible -CH 2 O- bridge between aryl moieties and was found to enhance the activity and selectivity of the inhibitors as shown in the original work [ 9 ] . Biophores #1 and #2 include aromatic moieties, whose main function is presumably to bind to the hydrophobic site of MAO.

  • Overall, high coverage and good predictive power by all models indicated that the database's biophores are not products of chance-correlation, but are relevant to the specific activity types they represent.

  • The most reliable biophores from each model were then selected as initial structural elements for the construction of new drug prototypes.


How many words do you know? Try our free vocabulary size test!


Search

Search for example sentences

Loading Loading...
Quantcast