Words similar to biophores

Example sentences for: biophores

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The latter group contains fewer biophores, but there are some insights of its mechanism of action and a structural analysis has been made for it [ 21 ] . Hence, glutamate-site NMDA antagonists (Figure 2B) were favored as a structural prototype since some NMDA antagonists from the former group (Figure 3A) express antagonistic activity toward dopamine receptors (e.g.
The best biophores were selected using the same criteria as those used to assess the NMDA and the MAO databases (Table 3#11-16).
Analysis of biophores #1, #2 (#4, #5) showed that both of them occur in substituted 5-[4-(benzyloxy) phenyl]-1,3,4-oxadiazol-2-(3H)-ones and their analogs (Figure 1), many of which are known to be strong MAO-B inhibitors [ 9 ] . Biophore #2 represents a flexible -CH 2 O- bridge between aryl moieties and was found to enhance the activity and selectivity of the inhibitors as shown in the original work [ 9 ] . Biophores #1 and #2 include aromatic moieties, whose main function is presumably to bind to the hydrophobic site of MAO.
More details will be given later during the discussion of the specific databases and their biophores.
To ensure compatibility we compared biophores and biophobes (fragments that are found to be responsible for molecular inactivity) across all three databases and found no collisions.