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Example sentences for: biophores
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The same criteria were used in the selection of the best biophores from the NMDA model as were described in the case of the MAO databases (Biophores #7-10, Table 3).
Biophores #8, #9, and #10 also occur in the NMDA antagonists that bind to glutamate-binding site of NMDA receptor (e.g.
The latter group contains fewer biophores, but there are some insights of its mechanism of action and a structural analysis has been made for it [ 21 ] . Hence, glutamate-site NMDA antagonists (Figure 2B) were favored as a structural prototype since some NMDA antagonists from the former group (Figure 3A) express antagonistic activity toward dopamine receptors (e.g.
Figure 3A) shows the generic structure of an NMDA antagonist that carries biophores #8 and #9 and B) the relative locations of biophores #8, #9 and #10 in the eliprodil molecular family.
The best biophores were selected using the same criteria as those used to assess the NMDA and the MAO databases (Table 3#11-16).
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