Example sentences for: biologic

How can you use “biologic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Given the well-known adverse metabolic consequences of overweight and obesity, the strong links with cardiovascular disease and several other serious illnesses, and the absence of any plausible adverse biologic consequences of maintaining normal weight (BMI 19 to 25), it seems prudent to continue advising adults to seek to maintain a weight within that range.

  • The most obvious biologic difference between men and women is the hormonal milieu, although other sex-specific factors cannot be ruled out.

  • Androgen exerts its biologic effects by binding to and activation of androgen receptor (AR) that trans-activates target genes through androgen responsive element (ARE) in the promoter of target genes [ 15 ] . In human breast cancer cells the effectiveness of retinoids in cell growth suppression was dictated by the presence of RAR [ 16 ] . Estrogen regulation of the expression of RAR α was mediated by interactions between estrogen receptor (ER) and estrogen responsive element (ERE) in the promoter of RAR α gene [ 17 ] . Because the DNA binding domains of steroid receptors including AR and ER are highly homologous, we postulated that similar mechanisms might also mediate the effect of androgen on RAR genes in prostate cells.

  • First, gene transfer results in continuous, rather than intermittent, protein delivery, thus maintaining a constant supply of IL-1Ra at a concentration sufficient to inhibit the biologic actions of IL-1.

  • Some individual measurements of therapeutic effect (tender-joint counts) and biologic activity (IL-6 levels) were observed.


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