Words similar to biologic
Example sentences for: biologic
How can you use “biologic” in a sentence? Here are some example sentences to help you improve your vocabulary:
First, gene transfer results in continuous, rather than intermittent, protein delivery, thus maintaining a constant supply of IL-1Ra at a concentration sufficient to inhibit the biologic actions of IL-1.
The evidence that adolescent diet may affect the risk of breast cancer derives from several lines of evidence [ 1 ] . Rates of breast cancer among Asian immigrants to the United States do not approach those of US white women until the second or third generation, suggesting that exposures during childhood and adolescence are important in establishing a higher risk of breast cancer [ 2 3 ] . Norwegian women who were adolescents during World War II, when average caloric intake decreased by 22%, have a reduced incidence of breast cancer, suggesting that energy restriction might affect risk [ 4 ] . Similarly, in animal models, energy restriction in the peripubertal period inhibits mammary tissue proliferation and reduces the subsequent risk of mammary tumors [ 5 6 ] . Exposure of rats to carcinogens before first pregnancy increases the incidence of mammary tumors compared with exposure after first pregnancy [ 7 ] . After differentiation of the mammary gland at the time of first full-term pregnancy of the rat, the rate of cell division decreases and length of the cell cycle increases, allowing more time for DNA repair [ 8 ] . This biologic phenomenon might explain the apparent vulnerability of the adolescent breast tissue to carcinogenic exposures.
Breast cancer incidence has been positively associated with socioeconomic status across race/ethnicity, geography, and time [ 19 20 21 22 23 ] . Recent data from California show that rates for white women in the highest socioeconomic quintile were 27% higher than the lowest quintile and were 13% higher than the overall rate [ 23 ] . However, understanding of the biologic factors mediating this association remains incomplete.
For analytic purposes, composite variables for the exposure classification of cases and controls were created based on the biologic construct for each major mode of transmission.
An interaction exists when the relationship between an independent variable x and an outcome variable y varies according to the value of another covariate z . The presence of a statistically significant interaction would suggest the presence of an underlying biologic effect modification and provide epidemiologic clues to the etiology and pathogenesis [ 23 ] .
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