Example sentences for: bioavailability

How can you use “bioavailability” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Fiber might affect the risk of breast cancer by decreasing estrogen levels; fiber binds estrogen excreted into the gastrointestinal tract and reduces enterohepatic circulation [ 17 18 ] . In addition, higher dietary fiber intake has been associated with higher plasma levels of sex-hormone-binding globulin, which can reduce the bioavailability of estrogens [ 19 ] . The potential mechanism of a protective effect of vegetable fat is more speculative: vegetable fat is a composite of multiple forms of fatty acids, some of which have been proposed to increase risk (such as C 18:2 n-6) whereas other specific fatty acids have been proposed to decrease risk (such as C 18:1 , the primary fatty acid in olive oil) [ 20 ] . More detail on the type and composition of the vegetable oil used is necessary to pursue this relation with greater precision.

  • These findings establish the bioavailability of the drug following this route of administration.

  • Structural variation (changing X, Y, and the position of the hydroxyl group) can be used for membrane permeability adjustment, enhancement of oral bioavailability and improvement of Blood-Brain Barrier penetration.

  • Because the M6P/IGF2R is believed to sequester and degrade IGF-II [ 10 ] , a decrease in M6P/IGF2R could result in decreased degradation and hence increased bioavailability of IGF-II to the IGF-I receptor, which mediates the growth-promoting effect of IGF-II.

  • The latter precursor has the advantage of small size and its activity is quite tolerant to derivatization at the para-position [ 22 ] , whereas the former is known to have high oral bioavailability and low toxic effects in rats [ 9 ] .


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