Example sentences for: bioavailability

How can you use “bioavailability” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • These findings establish the bioavailability of the drug following this route of administration.

  • Fiber might affect the risk of breast cancer by decreasing estrogen levels; fiber binds estrogen excreted into the gastrointestinal tract and reduces enterohepatic circulation [ 17 18 ] . In addition, higher dietary fiber intake has been associated with higher plasma levels of sex-hormone-binding globulin, which can reduce the bioavailability of estrogens [ 19 ] . The potential mechanism of a protective effect of vegetable fat is more speculative: vegetable fat is a composite of multiple forms of fatty acids, some of which have been proposed to increase risk (such as C 18:2 n-6) whereas other specific fatty acids have been proposed to decrease risk (such as C 18:1 , the primary fatty acid in olive oil) [ 20 ] . More detail on the type and composition of the vegetable oil used is necessary to pursue this relation with greater precision.

  • Thus, they were tested against databases predicting plasma protein binding affinity [ 32 ] , oral bioavailability and urine excretion (unpublished results).

  • The effect of IFNβ on MX1, IFNAr1, and STAT2 was observed for two years in all patients, suggesting that the response did not depend on IFNβ bioavailability.

  • M6P/IGF2R allelic loss would therefore result in enhanced cellular bioavailability of this potent growth factor, thereby potentially increasing both cell proliferation and resistance to apoptosis [ 29 ] . The M6P/IGF2R also facilitates the activation of TGFβ, a potent cell growth inhibitor that is secreted in an inactive form (reviewed in [ 15 16 ] ). M6P/IGF2R mutation is therefore one mechanism by which cancer cells can become refractory to TGFβ's mitoinhibitory effect.


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