Words similar to bim
Example sentences for: bim
How can you use “bim” in a sentence? Here are some example sentences to help you improve your vocabulary:
First, the PKC activation inhibitor, BIM, did not prevent either the PMA-induced hyperpolarization (Figs.
7), supporting the hypothesis that activation of PKC synergizes secretory process activated by the glucose stimulation [ 3 4 5 ] . BIM is known to selectively inhibit α and β PKC isotypes [ 25 ] , and rat pancreatic β-cells possess at least one PKC isotype [ 2 ] . In fact, in this study, the treatment of islets with BIM reversed the PMA effect on insulin secretion (Fig.
The PMA effects with or without BIM on insulin secretion were measured by using immuno-reactive insulin (IRI) and stored at -20°C until the assay.
Recent work has shown that the Bcl-2 family regulates mitochondrial homeostasis during apoptosis [ 1 ] . Pro-apoptotic members, including Bax, Bak, Bid, and Bim, promote the release of death-inducing proteins, such as cytochrome c [ 2 3 ] , smac [ 4 ] , and endonuclease G [ 5 ] , from mitochondria while anti-apoptotic members, such as Bcl-2 and Bcl-X L , inhibit this release.
In two experiments, higher concentration (10 μM) of BIM failed to prevent PMA-induced inhibition too (data not shown).
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