Words similar to bile
Example sentences for: bile
How can you use “bile” in a sentence? Here are some example sentences to help you improve your vocabulary:
asbt, apical sodium/bile acid cotransporter; GCA, glycocholic acid; GCDCA, glycochenodeoxycholic acid; HBAB, human bile acid binder; LDH, lactate dehydrogenase; PI3K, phosphatidylinositol 3-kinase; TCA, taurocholic acid, TCDCA, taurochenodeoxycholic acid
In hamsters, rats and mice, increases and decreases in bile acid absorption at the brush border membrane are mediated by an up- or down-regulation in IBAT gene transcription [ 33 34 ] . In several rodent species including mice, regulation of IBAT is clearly dependent on intraluminal bile acid concentrations and occurs via a negative feedback mechanism [ 33 34 35 ] . Feeding of bile acids suppresses transcription of IBAT mRNA and reduces IBAT protein abundance; feeding of the bile acid binder cholestyramine has the opposite effect.
The WKY rat also carries this mutation and a high dietary intake of phytosterols will also increase the blood pressure and decrease the density of platelets, though to a lower extent than that observed in SHRSP rats [ 20 ] . These data support a pathological role of elevated plant sterols in these rats and support the notion that the STSL loci evolved to not only allow for the excretion of cholesterol into bile, but also to keep 'xeno-sterols' from accumulating in the body.
Since bile acids undergo enterohepatic circulation, it would be reasonable to expect the existence of the same mechanism in other cell types that naturally transport bile acids, such as ileocytes and cholangiocytes [ 34 35 ] . The last few years have brought significant advances in our understanding of bile acid transport in liver and intestinal cells.
35 cells reached steady state within 10 min (Figure 3D), implying the presence of a pathway for bile acid efflux in CHO cells.
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